Ex parte BONUTTI et al. - Page 6




                  Appeal No. 1998-2637                                                                                        Page 6                      
                  Application No. 08/470,142                                                                                                              


                           The test for obviousness is what the combined teachings of the prior art would have                                            
                  suggested to one of ordinary skill in the art.  See, for example, In re Keller,                                                         
                  642 F.2d 413, 425, 208 USPQ 871, 881 (CCPA 1981).  In establishing a prima facie case                                                   
                  of obviousness, it is incumbent upon the examiner to provide a reason why one of ordinary                                               
                  skill in the art would have been led to modify a prior art reference or to combine reference                                            
                  teachings to arrive at the claimed invention.  See Ex parte Clapp, 227 USPQ 972, 973                                                    
                  (Bd. Pat. App. & Int. 1985).  To this end, the requisite motivation must stem from some                                                 
                  teaching, suggestion or inference in the prior art as a whole or from the knowledge                                                     
                  generally available to one of ordinary skill in the art and not from the appellants' disclosure.                                        
                  See, for example, Uniroyal, Inc. v. Rudkin-Wiley Corp.,                                                                                 
                  837 F.2d 1044, 1052, 5 USPQ2d 1434, 1439 (Fed. Cir.), cert. denied, 488 U.S. 825                                                        

                  (1988).                                                                                                                                 
                                                                           (2)                                                                            
                           The first of the rejections under Section 103 is that independent claim 57 and                                                 
                  dependent claims 58-60 and 67 are unpatentable over Melker in view of Lee.  Claim 57                                                    
                  recites a method comprising a first step of providing a cannula with a sheath at least                                                  
                  partially enclosing a plurality of wires “having leading end portions at a leading end portion                                          
                  of the sheath,” engaging a surface area of the side wall of a vessel “with at least a portion                                           
                  of the leading end portion of at least one of the wires and at least a portion of the leading                                           









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