Ex Parte PARADISSIS et al - Page 11


                 Appeal No. 2001-1909                                                        Page 11                    
                 Application No. 09/016,786                                                                             

                        At the time of the amendment, appellants stated that basis for the                              
                 amendment could be found on page 10, lines 11-27 of the specification.                                 
                 However, that passage (see Background supra) does not disclose taking a                                
                 vitamin at night.  The passage indicates that significant nerve tissue repair                          
                 occurs during sleep and that “[c]onventional administration of vitamins during the                     
                 daytime fails to account for the significant need for B complex Vitamins at night.”                    
                 However, this passage does not say when the vitamin should be taken. That is                           
                 explained elsewhere in the specification.                                                              
                        In three places, the specification mentions “administering” the vitamin at                      
                 “night”:                                                                                               
                     · “administering the agent in multiple dosages during the daytime and at                           
                        night” (p. 4, lines 16-17);                                                                     
                     · “administering the agent in multiple dosages during the daytime and at                           
                        night” (p. 7, lines 15-16); and,                                                                
                     · “the total daily dosage may be divided and administered in portions during                       
                        the day if desired or at one time, morning, afternoon, night” (p. 14, lines                     
                        30-32 ).                                                                                        
                 In none of these statements is “night” given any particular significance. “Night” is                   
                 just one of a number of possible times for introducing the vitamin into the body,                      
                 the purpose being to release the vitamin over a 24-hour period.                                        
                        Reading the passage of p. 10, lines 11-27 in light of these disclosures, it                     
                 becomes clear that appellants are seeking to overcome the short duration of                            
                 present conventional dosages of vitamins; i.e., they do not last long enough to                        
                 still be present in the human body during sleep (usually at night) when the                            
                 vitamin B complex has the greatest impact on nerve tissue repair. Appellants                           
                 appear to solve this problem, not by introducing a vitamin at night per se, but by                     





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