Ex Parte PARADISSIS et al - Page 12


                 Appeal No. 2001-1909                                                        Page 12                    
                 Application No. 09/016,786                                                                             

                 causing the vitamin to be released over a “substantially continuous 24-hour”                           
                 period to include the night, thereby extending the bioavailability of the vitamin to                   
                 coincide with the act of sleeping and concurrently optimizing nerve tissue repair.                     
                        For the foregoing reasons, examiner should first interpret the claims in                        
                 light of the specification, being certain that the interpretation to be applied                        
                 complies with the written description requirement of the first paragraph of 35                         
                 U.S.C. § 112. Based on that interpretation, examiner should then analyze the                           
                 scope of the claims before making a patentability determination over the prior                         
                 art.                                                                                                   
                        Reason #6                                                                                       
                        One of the arguments that appellants make in their Brief (see p. 37), in                        
                 rebuttal to the rejections of the claims under 35 U.S.C. § 103 over the primary                        
                 reference Koltringer, is that Koltringer discloses two active ingredients (Gingko                      
                 bilobae extract and a vitamin B complex) in contradistinction with the claimed                         
                 process of administering a vitamin B complex alone. Examiner’s response                                
                 (Examiner’s Answer, p. 4) is that “applicant has not shown that the other                              
                 components in prior art teachings are detrimental in instant compositions.”                            
                        Notwithstanding that it is examiner’s burden, not appellants’, to establish a                   
                 prima facie case of obviousness and therefore it is examiner who has the burden                        
                 of showing that why one of ordinary skill would be led to modify the Koltringer                        
                 method to solely administer a vitamin B complex, the use of a vitamin B as the                         
                 sole active ingredient is well known.  To that end, we cite U.S. Patent 4,945,083                      
                 (Jansen et al.) and U.S. Patent 4,432,975 (Libby).  We also cite a publication                         





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