Ex Parte LUTJENS et al - Page 7


          Appeal No. 2001-2093                                                        
          Application No. 09/054,134                                                  

          278, 280 (CCPA 1976); In re Boe, 355 F.2d 961, 965, 148 USPQ                
          507, 510 (CCPA 1966).                                                       
               Regarding the use of concentrated sulfuric acid in DE ’715             
          (appeal brief, page 4), the appellants’ specification states                
          that strong sulfuric acid may be used to control the pH to the              
          recited range, as we pointed out above.  Accordingly, we see no             
          basis for concluding that the use of concentrated sulfuric acid             
          favors a determination of nonobviousness.                                   
               The appellants rely on the teachings of Seymour, Cram,                 
          Morrison, and The Encyclopedia of Polymer Science and Technology            
          for the proposition that the “reactions of small molecules are              
          not necessarily predictive of reactions of polymers.”  (Appeal              
          brief, page 6.)  We agree with the appellants that the specific             
          reaction conditions suitable for polymers may not necessarily be            
          the same as the conditions for compounds.  Nevertheless, the                
          prior art suggests that the same variables would affect the                 
          results for alkylation reactions of tertiary amines, regardless             
          of whether polymers or compounds are used as the starting                   
          materials.  Thus, the prior art as a whole would have fairly                
          suggested to one of ordinary skill in the art that temperature              
          and pH are result-effective variables in the alkylation of                  
          polymers containing tertiary amines.  Accordingly, it is our                
          judgment that the discovery of workable or even optimum                     

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