Ex Parte QUAY - Page 11




          Appeal No. 2000-0827                                                        
          Application 08/466,104                                                      


          gases are among only ten gases recited in the originally filed              
          claims, of which claims 5, 11, and 12 read: 4                               
                    5.  Contrast media of claim 1 wherein the gas is                  
               octafluoropropane.                                                     
                    11.  Contrast media of claim 1 wherein the gas is                 
               decafluorobutane.                                                      
                    12.  Contrast media of claim 1 wherein the gas is                 
               dodecafluoropentane.                                                   
               For the foregoing reasons, we agree with Appellant that the            
          application as filed adequately demonstrates a preference for               
          contrast agents containing the three claimed gases.                         
               The examiner asserts that the application discloses "at                
          least eleven different approaches" suitable for forming the                 
          microbubbles in Appellant's contrast agents (Answer at 7,                   
          ll. 1-4).  Assuming for the sake of argument that the examiner is           
          correct on this point, that number is not, in our view,                     
          sufficient to satisfy the examiner's initial burden of proof to             
          show a lack of written description support using the Ruschig                
          rationale, since the claimed gases have been shown to be                    
          preferred gases.  In any event, for the following reasons the               




               4  The gases are recited in the other original claims are              
          sulfur hexafluoride (claim 3), hexafluoropropylene (claim 4),               
          hexafluoroethane (claim 6), octafluoro-2-butene (claim 7),                  
          hexafluoro-2-butyne (claim 8), hexafluorobuta-1,3-diene                     
          (claim 9), and octafluorocyclobutane (claim 10).                            
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