Ex Parte DISMUKES et al - Page 13


              Appeal No. 2001-0233                                                                                       
              Application 08/668,640                                                                                     
              that criticality (Reply Brief, page 2, lines 10 et seq.).  The Examiner, on the other hand,                
              has put forth a prima facie case of obviousness vis-à-vis Takeda alone.  The Examiner                      
              further remains unpersuaded by the evidence, noting that the instant claims preclude                       
              the presence of materials which are initially silicon containing, while the ‘759 patent                    
              urged as evidence requires them.  Further, the Examiner challenges the                                     
              correspondence between the materials of the ‘759 patent and the instant claims.                            
              Finally, as regards the instant specification, the Examiner asserts that no criticality is                 
              established for quantity or particle size  (See, generally, the Examiner’s Answer, page 5,                 
              line 10 – page 6, line 15).                                                                                
                     We note that it is not inventive to discover optimum or workable ranges by                          
              routine experimentation, and appellants have the burden of proving any criticality.  In re                 
              Boesch, 617 F.2d 272, 276, 205 USPQ 215, 218-19 (CCPA 1980); In re Aller, 220 F.2d                         
              454, 456, 105 USPQ 233, 235 (CCPA 1955).  There are certain elements of this burden                        
              which must be met once a prima facie case of obviousness has been established.                             
                     First, we note that appellants must show that the claimed range is critical,                        
              generally by showing that the claimed range achieves unexpected results relative to the                    
              prior art range. In re Woodruff, 919 F.2d 1575, 1578, 16 USPQ2d 1934, 1936 (Fed. Cir.                      
              1990).  Second, one relying on data to establish unexpected results has a burden of                        
              establishing that unexpected results are actually obtained and the significance of those                   
              results to one having ordinary skill in the art.  Cf. In re Klosak, 455 F.2d 1077, 1080, 173               
              USPQ 14, 16 (CCPA 1972) (inventor must show that the results claimed to be obtained                        
              with a claimed invention are actually obtained with the invention).  Third, in order to                    
              establish unexpected results for a claimed invention, objective evidence of                                


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