Ex Parte TESHIMA et al - Page 3


                Appeal No. 2001-1160                                                  Page 3                  
                Application No. 08/479,977                                                                    

                effectiveness against termites (Coptotermes formosanus).  The results (Table 2)               
                show that MGK-264 completely lost effectiveness after two months, and                         
                permethrin caused only 30% mortality after three months.  The combination of                  
                MGK-264 and permethrin, however, caused 100% termite mortality even after                     
                three months’ storage.  Appellants concluded that the “composition is a termite-              
                controlling agent excellent in the persistence of efficacy, and particularly it is            
                extremely effective also in use for soil treatment.”  Specification, page 8.                  
                                                 Discussion                                                   
                      The claims are directed to a method for controlling termites by applying a              
                combination of a pyrethroid (e.g., permethrin) and MGK-264 to termite-infested                
                soil or to wood.  The examiner rejected the claims as obvious over Joyce and                  
                Richardson:                                                                                   
                      The Joyce et al. reference teaches that the claimed combination of                      
                      permethrin and MGK-264 is old and known for [its] synergistic                           
                      insecticidal activity.  The [Richardson] reference teaches that the                     
                      claim designated permethrin is an old insecticide effective against                     
                      termites.  See page 4, line 13, wherein termites are disclosed; page                    
                      3, line 1, wherein, permethrin is the preferred insecticide; and page                   
                      2, line 2, wherein timber is treated.  The prior art clearly teaches                    
                      that permethrin is effective as a termite insecticide.  The prior art                   
                      also teaches that the combination of permethrin and MGK-264 is                          
                      old and known for its synergistic insecticidal properties.  Therefore,                  
                      one skilled in the art would find ample motivation from the prior art                   
                      supra to use the claimed combination of compounds against the                           
                      target insects and locus of the instant application with a reasonable                   
                      expectation that said compounds would be effective to combat said                       
                      target insects.                                                                         
                Examiner’s Answer, page 4.                                                                    
                      Appellants argue that the examiner has not made out a prima facie case                  
                of obviousness and that, in any case, “any possible prima facie obviousness                   





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