Ex Parte LACKIE et al - Page 4




               Appeal No. 2001-2401                                                                                                
               Application 08/277,225                                                                                              
               Woods et al. (Woods)                          4,469,787                      Sep. 4, 1984                           
               Freytag et al. (Freytag), “Affinity-column-mediated immunoenzymometric assays:                                      
               Influence of affinity-column ligand and valency of antibody-enzyme conjugates,” Clin.                               
               Chem., Vol. 30, No. 9, pp. 1494-1498 (1984)                                                                         
               Friguet et al. (Friguet), “Measurements of the true affinity constant in solution of                                
               antigen-antibody complexes by enzyme-linked immunosorbent assay,” Journal of                                        
               Immunological Methods, Vol. 77, pp. 305-319 (1985)                                                                  
               Pollema et al. (Pollema), “Sequential injection immunoassay utilizing immunomagnetic                                
               beads,” Anal. Chem., Vol. 64, pp. 1356-1361 (1992)                                                                  

               Grounds of Rejection                                                                                                
                       Claims 1-10 stand rejected under 35 U.S.C. § 112, second paragraph as being                                 
               indefinite.                                                                                                         
                       Claims 1-5, 8-14, 16-21 and 23-25 stand rejected under 35 U.S.C. § 103 as                                   
               obvious over Pollema in view of Friguet and Woods.                                                                  
                       Claims 6-7, 22 and 25 stand rejected as obvious over Pollema in view of Friguet                             
               and Woods, in further view of Freytag.                                                                              
                       We reverse the rejection of claims 1-10 under 35 U.S.C. § 112, second                                       
               paragraph and the rejections under 35 U.S.C. § 103.                                                                 


                                                         DISCUSSION                                                                
                       In reaching our decision in this appeal, we have given careful consideration to                             
               the appellants’ specification and claims, to the applied prior art references, and to the                           
               respective positions articulated by the appellants and the examiner.                                                

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