Ex Parte STACHE et al - Page 4


                Appeal No. 2003-1034                                                  Page 4                 
                Application No. 08/897,455                                                                   

                render any species that falls within it obvious.  See In re Jones, 958 F.2d 347,             
                350, 21 USPQ2d 1941, 1943 (Fed. Cir. 1992); In re Baird, 16 F.3d 380, 382-83,                
                29 USPQ2d 1550, 1552 (Fed. Cir. 1994).  There need be some teaching or                       
                suggestion to lead the ordinary artisan to select the claimed compound.  See                 
                Baird, 16 F.3d at 382, 29 USPQ2d at 1552.  The disclosure of                                 
                phenylproprionates in a long laundry list of acceptable substituents does not, in            
                and of itself, lead one to the claimed compounds.                                            
                      As noted by the examiner in the response to arguments, however,                        
                Djerassi specifically exemplifies a compound having a phenyl group at the 21                 
                position, the 17,21-dienzoates in Example XII.  See Examiner’s Answer, page 7.               
                Thus the issue becomes does the exemplification of the benzoate at the 21                    
                position, along with the disclosure of the phenylproprionate as one of the                   
                possible substituents at the 21 position, fairly suggest the claimed compounds.              
                We find that the issue was not fairly before appellants, as citing to that specific          
                example of Djerassi in the response to arguments in the Examiner’s Answer can                
                not be interpreted as being part of the rejection on appeal.  See, e.g., In re               
                Hedges, 783 F.2d 1038, 1039, 228 USPQ 685, 686 (Fed. Cir. 1986) (noting that                 
                the court would not condone the presentation of new grounds of rejection for the             
                first time on appeal).                                                                       
                      The examiner has thus failed to address relevant teachings of the Djerassi             
                reference in the context of the rejection, and thus the fact finding is incomplete           
                and the issue is not susceptible to meaningful review.  Because the rejection                
                failed to rely on those teachings of the Djerassi reference, we vacate the                   





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