Ex Parte YAN et al - Page 2




          Appeal No. 2003-1470                                                        
          Application No. 08/847,763                                                  

          and which comprises surfaces capable of contacting vessel walls             
          of the lumen and surfaces incapable of contacting the vessel                
          walls upon implantation.  The device further comprises a coating            
          exclusively deposited on surfaces of the device that are                    
          incapable of contacting the vessel walls whereby a toxic effect             
          to the patient’s vasculature is avoided (i.e., by avoiding                  
          contact of the coating with the vessel walls).  This appealed               
          subject matter is adequately illustrated by independent claim 1             
          which reads as follows:                                                     
               1. A device, comprising:                                               
               a body that is implantable within a lumen of the vascular              
          system, such lumen being defined by vessel walls and wherein said           
          body has surfaces capable of contacting said vessel walls and               
          surfaces incapable of contacting said vessel walls upon                     
          implantation; and                                                           
               a coating devoid of heparin exclusively deposited on                   
          surfaces of said body that are incapable of contacting said                 
          vessel walls wherein such coating is formed of material that                
          adheres to said body and includes function groups to attract                
          heparin and form a bond therewith when such material is exposed             
          to a solution containing heparin                                            
               whereby a toxic effect to the patient’s vasculature is                 
          avoided.                                                                    
               The references set forth below are relied upon by the                  
          examiner as evidence of obviousness:                                        
          Ward et al. (Ward)            4,164,524      Aug. 14, 1979                  
          Hu et al.   (Hu)              4,865,870      Sep. 12, 1989                  

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