Ex Parte WILDING et al - Page 10


               Appeal No. 2003-1103                                                Page 10                 
               Application No. 09/212,029                                                                  

                      Consonance requires that the line of demarcation between the                         
                      ‘independent and distinct inventions’ that prompted the restriction                  
                      requirement be maintained.  Though the claims may be amended,                        
                      they must not be so amended as to bring them back over the line                      
                      imposed in the restriction requirement.  Where that line is crossed                  
                      the prohibition of the third sentence of Section 121 does not apply.                 
               Gerber Garment Technology Inc. v. Lectra Systems Inc., 916 F.2d 683, 688, 16                
               USPQ2d 1436, 1440 (Fed. Cir. 1990).  As stated above, withdrawn claim 10 and                
               instant claims 44 and 46 contain the same limitation, “means for detecting said             
               amplified polynucleotide.”  Reply Brief, Appendix.  Because instant claims 44 and           
               46 are consonant with the restricted and subsequently withdrawn claim 10 of the             
               ‘199 application, the ‘392 patent is not available as a reference for rejecting the         
               instant claims under the judicially-created doctrine of obviousness-type double             
               patenting.  The examiner’s rejection is reversed.                                           
                                                                                                          
                                                 Summary                                                   

                     We reverse the rejection under 35 U.S.C. § 102(e) because Schnipelsky                
               does not reasonably appear to disclose a device for amplifying a preselected                
               polynucleotide in a sample by conducting a polynucleotide polymerization                    
               reaction that satisfies all of the limitations of appellants’ claims.  Further, we          














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