Appeal No. 2003-2017 Page 2
Application No. 09/802,116
The examiner relies on the following references:
Van de Loo et al., “An Oleate 12-hydroxylase from Ricinus Communis L. is a
Fatty acyl Desaturase Homolog,” Proc. Natl. Acad. Sci., Vol. 92, pp. 6743-6747
(1995)
Smith et al., “The Challenges of Genome Sequence Annotation or ‘The devil is in
the details’,” Nature Biotechnology, Vol. 15, pp.1222-1223 (1997)
Broun et al., “Catalytic Plasticity of Fatty Acid Modification Enzymes Underlying
Chemical Diversity of Plant Lipids,” Science, Vol. 282, pp. 1315-1317 (1998)
Seki et al., “Structure, Expression Profile and Chromosomal Location of an Isolog
of DNA-PKcs Interacting Protein (KIP) Gene,” Biochimica et Biophysica Acta,
Vol. 1444, pp. 143-147 (1999)
Brenner, “Errors in Genome Annotation,” TIG, Vol. 15, No.4, pp. 132-133 (1999)
Bork, “Powers and Pitfalls in Sequence Analysis: The 70% Hurdle,” Genome
Research, Vol. 10, pp. 398-400 (2000)
NCI-CGAP, National Cancer Institute, Cancer Genome Anatomy Project,
AW295492 (2000)
Seki et al., GenEMBL accession number AB012955 (nucleotide), BAA33584
(polypeptide) (1999)
Saito et al., GenEMBL accession number AB016080 (1999)
Hayashi et al., GenBank accession number NM 054113 and NP 473454 (2002)
Claims 1 and 3 stand rejected under 35 U.S.C. § 101 as lacking
patentable utility, and under 35 U.S.C. § 112, first paragraph, as nonenabled.
We affirm.
Background
The specification discloses a cDNA encoding a putative human protein,
generically referred to as an NHP (for “novel human protein”), that “shares
structural similarity with animal (DNA-dependent) protein kinase interacting
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