Ex Parte SHAWVER et al - Page 1



                         The opinion in support of the decision being entered today was not written            
                                for publication and is not binding precedent of the Board.                     

                                                                                    Paper No. 52               

                       UNITED STATES PATENT AND TRADEMARK OFFICE                                               
                                                __________                                                     

                            BEFORE THE BOARD OF PATENT APPEALS                                                 
                                         AND INTERFERENCES                                                     
                                                 __________                                                    
                                        Ex parte LAURA K. SHAWVER,                                             
                                             JOHN W. BRANDIS,                                                  
                                               ELAINA MANN,                                                    
                                           MIRIAM E.C. HANCOCK,                                                
                                         RONALD P. MISCHAK, and                                                
                                             JOHN J. MONAHAN                                                   
                                                 __________                                                    
                                            Appeal No.  2004-0005                                              
                                         Application No. 07/644,361                                            
                                                 __________                                                    
                                           HEARD: March 4, 2004                                                
                                                 __________                                                    
             Before WINTERS, WILLIAM F. SMITH, and GREEN, Administrative Patent Judges.                        
             WILLIAM F. SMITH, Administrative Patent Judge.                                                    
                                           DECISION ON APPEAL                                                  
                   This is an appeal under 35 U.S.C. § 134 from the examiner’s final rejection of              
             claims 1 through 10 and 13 through 24, all the claims pending in the application.  Claims         
             1 and 9 are representative of the subject matter on appeal and read as follows:                   
                   1.  A drug combination cytoxic to tumor cells expressing c-erbB-2 protein                   
             comprising (a) an anti-neoplastic agent and (b) a molecule, not conjugated to the anti-           
             neoplastic agent, that binds said c-erbB-2 protein on the tumor cells and induces an              
             increase in the phosphorylation of c-erbB-2 protein when placed in contact with the               
             tumor cells.                                                                                      







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