Ex Parte SADELAIN et al - Page 5


                Appeal No. 2004-1930                                                   Page 5                  
                Application No. 08/940,544                                                                     

                within the scope of the present invention, without inference or guesswork.”  Id. at            
                5.                                                                                             
                      Again, we do not agree with appellants’ reasoning.  A patent disclosure                  
                need not set forth a compound with such specificity such that the compound                     
                could be claimed in order to serve as an anticipatory reference under 35 U.S.C. §              
                102(b).  See In re Schaumann, 572 F.2d 312, 317, 197 USPQ 5, 10 (CCPA                          
                1978).  We thus find that one skilled in the art, upon reading the Eshhar                      
                disclosure, would envisage the fusion protein encoded by the polynucleotide of                 
                claim 1, and “it is of no moment that each compound is not specifically named or               
                shown by structural formula in that publication.”  In re Petering, 301 F.2d 676,               
                681-82, 133 USPQ 275, 280 (CCPA 1962); see also In re Schaumann, 572 F.2d                      
                at 317, 197 USPQ at 10 (noting that In re Arkley “should not be interpreted as                 
                establishing a new test for determining whether an invention has been described                
                in a reference within the meaning of 35 U.S.C. § 102. . . .  It was not this court’s           
                intention in Arkley to effect a change in the accepted definition of ‘anticipation,’ a         
                term of art meaning ‘the disclosure in the prior art of a thing substantially identical        
                with the claimed invention.’”).                                                                
                      Appellants argue further that Eshhar does not provide an enabling                        
                disclosure.  See Appeal Brief, page 5.  According to appellants, Eshhar does not               
                provide any examples that relate to CD28 containing fusion proteins.  In addition,             
                appellants contend that the disclosure of a scFV-CD16α fusion, along with the                  
                “mere mention of CD28” is insufficient to provide an enabling disclosure, as the               
                examiner has provided “[n]o indication of similarities between CD28 and CD16.”                 





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