Ex Parte Kozlov et al - Page 2




             Appeal No. 2005-0548                                                                              
             Application No. 09/839,164                                                                        


             that the claims stand or fall together.  Accordingly, for purposes of this appeal, we will        
             consider the issues as they apply to claim 30 which is representative of the subject              
             matter on appeal.                                                                                 
                   Claim 30 reads as follows:                                                                  
                          30.   A pharmaceutical composition consisting essentially of the alpha               
                   globin chain of hemoglobin in a pharmaceutically acceptable carrier, wherein the            
                   composition is suitable for subcutaneous administration and said alpha globin               
                   chain is present in an amount of 0.1 mg to 6 g.                                             

                   The references relied upon by the examiner are:                                             
                   Hoffman et al.            5,449,759                 Sep. 12, 1995                           
                          (Hoffman)                                                                            
                   Tame et al. (Tame), Functional Role Of The Distal Valine (E11) Residue Of A                 
                   Subunits In Human Haemoglobin, 1991, J. Mol. Biol. 218:761-767                              

                   The claims stand rejected as follows:                                                       
             I.   Claims 30-32 stand rejected under 35 U.S.C. § 112, second paragraph, as being                
             indefinite for failing to particularly point out and distinctly claim the subject matter which    
             the Appellants regard as the invention.                                                           
             II.  Claims 30-32 stand rejected under 35 U.S.C. § 102(b) as being anticipated by Tame.           
             III.  Claims 30-32 stand rejected under 35 U.S.C. § 102(b) as being anticipated by                
             Hoffman.                                                                                          




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