Ex Parte Kozlov et al - Page 7




                Appeal No. 2005-0548                                                                                                         
                Application No. 09/839,164                                                                                                   
                        We find this argument unpersuasive.                                                                                  
                        Anticipation requires that each and every limitation set forth in a claim be                                         
                present, either expressly or inherently, in a single prior art reference.  In re Robertson,                                  
                169 F.3d 743, 745, 49 USPQ2d 1949, 1950 (Fed. Cir. 1999); Celeritas Techs. Ltd v.                                            
                Rockwell Int’l Corp., 150 F.3d 1354, 1360, 47 USPQ 1516, 1522 (Fed. Cir. 1998);                                              
                Verdegaal Bros., Inc. v. Union Oil Co., 814 F.2d 628, 631, 2 USPQ2d 1051, 1053 (Fed.                                         
                Cir. 1987); Lindemann Maschinenfabrik GMBH v. American Hoist and Derrick Co., 730                                            
                F.2d 1452, 1458, 221 USPQ 481, 485 (Fed. Cir. 1984).                                                                         
                        Here, if we accept the appellants’ interpretation of representative claim 30 (i.e.,                                  
                that it is directed to a pharmaceutical composition having 0.1 mg to 6 gm of alpha globin                                    
                regardless of its concentration in the composition (Brief, p. 3)), then we find that said                                    
                claim is anticipated by the teachings of the applied prior art.  That is, contrary to the                                    
                appellants’ argument, we find that Tame discloses a milliliter of buffer containing 5 mg                                     
                of alpha globin.  Tame, p. 763, col. 1, para. 2.  Tame further discloses a milliliter of                                     
                buffer containing 0.25 mg of alpha globin.  Id.  Both compositions are within the                                            
                concentration range set forth in claim 30.  In addition, we agree with the examiner that                                     
                Hoffman discloses two pharmaceutical compositions consisting essentially alpha globin                                        
                which are  within the scope of the claim; viz., a milliliter of buffer containing 5 mg of                                    
                alpha globin and a milliliter of buffer containing 0.3 gm [sic, 3 mg?] of alpha globin.                                      





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