Ex Parte Mothrath et al - Page 4


                     Appeal No. 2006-1273                                                                                                           
                     Application No. 10/420,400                                                                                                     

                     (e.g., yield, purity, etc.) ….”  (Final Office Action, page 7).  According to the Examiner:                                    
                     “Generally, differences in concentration or temperature will not support the patentability                                     
                     of subject matter encompassed by the prior art unless there is evidence indicating such                                        
                     concentration or temperature is critical.  ‘[W]here the general conditions of a claim are                                      
                     disclosed in the prior art, it is not inventive to discover the optimum or workable ranges                                     
                     by routine experimentation.’  In re Aller, 220 F.2d 454, [456,] 105 USPQ 233, 235                                              
                     (CCPA 1955) (Claimed process which was performed at a temperature between 40° C                                                
                     and 80° C and an acid concentration between 25 and 70% was held to be prima facie                                              
                     obvious over a reference process which differed from the claims only in that the reference                                     
                     process was performed at a temperature of 100° C and an acid concentration of 10%.).”                                          
                     (Final Office Action, page 7 (emphasis in original).)                                                                          
                              The Examiner also recognized that “König et al. differ[] from the instant                                             
                     invention in that the alcohol is added during the reaction whereas the instant invention                                       
                     adds the alcohol after the reaction.”  (Examiner’s Ans., page 4.)                                                              
                              Nevertheless, the Examiner maintained her § 103(a) rejection:  “It would have                                         
                     been obvious to one of ordinary skill in the art to have added the alcohol before, during or                                   
                     after the reaction since König et al. teach the reaction can be performed without the                                          
                     alcohol and therefore it is clear that the addition of the alcohol is not for the reactivity of                                
                     the process but to form a biphasic system” to facilitate the separation of the product and                                     
                     obtain a purer product.  (Id. at 4.)                                                                                           
                                                                 DISCUSSION                                                                         
                              For the reasons set forth in the Final Office Action, the Examiner’s Answer and                                       
                     below, we sustain the rejection of all the claims in this appeal.                                                              


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