Ex Parte Ayisi - Page 2


                  Appeal No. 2006-1608                                                               Page 2                     
                  Application No. 09/978,593                                                                                    



                          Claims 20, 22, 31 and 32 stand rejected under 35 U.S.C. § 112, first                                  
                  paragraph, on the grounds that the specification fails to provide an enabling                                 
                  disclosure.  In addition, claims 20 and 31 stand rejected under 35 U.S.C. §                                   
                  102(b) as being anticipated by El-Said1 as evidenced by Merck.2  After careful                                
                  review of the record and consideration of the issues before us, we reverse both                               
                  rejections.                                                                                                   
                                                        DISCUSSION                                                              
                          Claims 20, 22, 31 and 32 stand rejected under 35 U.S.C. § 112, first                                  
                  paragraph, “because the specification, while being enabling for inhibiting HIV viral                          
                  replication in Vero cells and Molt4 clone 8 cells with an extract of O. gratissimum,                          
                  does not reasonably provide enablement for the O. gratissimum extract to inhibit                              
                  HIV viral replication in a mammal or any other cell line.  The specification does                             
                  not enable any person skilled in the art to which it pertains, or with which it is                            
                  most nearly connected, to practice the invention commensurate in scope with                                   
                  these claims.”  Examiner’s Answer, page 3.                                                                    







                                                                                                                                
                  1 El-Said et al. (El-Said), “An investigation into the efficacy of Ocimum gratissimum as used in              
                  Nigerian native medicine,” Planta Medicine, pages 195-200 (1969).                                             
                  2 Merck Manual (Merck), Beers et al., editors, published by Merck Research Laboratories,                      
                  Whitehouse Station, NJ, pp. 1293-1296, 1303-1306, 1312-1323, 2320-2324 and 2341-2343                          
                  (1999).                                                                                                       





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