Ex Parte Austrup et al - Page 4


             Appeal No. 2006-2568                                                              Page 4                
             Application No. 09/744,866                                                                              

             limitation its “broadest reasonable interpretation consistent with the specification.”  In re           
             Sneed, 710 F.2d 1544,1548, 218 USPQ 385, 388 (Fed. Cir. 1983) (emphasis added).                         
                    On page 13, the specification states that “it is also possible to modify the cancer              
             cells in the cell suspension prior to the screening process, for example by labeling, by                
             attaching particles, by triggering aggregation and/or cluster formation using, for                      
             example, suitable antibodies, enzymes, lectins, other ligands and/or receptors or                       
             crosslinking reagents, by fixing and by inducing other defined states.”  We interpret this              
             to mean that the cancer cells may be modified – using, for example, antibodies,                         
             enzymes, lectins, other ligands, other receptors, or crosslinking reagents – by labeling,               
             attaching particles, triggering aggregation, and/or triggering cluster formation.  In                   
             addition, the cancer cells may be modified by fixing or by inducing other defined states.               
                    We interpret claims 24 and 28 to exclude the limitations discussed on page 13 of                 
             the specification.  That is, we interpret claims 24 and 28 to require that the tumor cells              
             are not modified – using antibodies, enzymes, lectins, other ligands, other receptors, or               
             crosslinking reagents – by labeling, attaching particles, triggering aggregation, and/or                
             triggering cluster formation and are not modified by fixing.                                            
             2.  Written Description                                                                                 
                    The examiner rejected claims 24 and 28 under 35 U.S.C. § 112, first paragraph,                   
             for failing to comply with the written description requirement.  Specifically, the examiner             
             argued that the specification does not support the recitation in claims 24 and 28                       
             requiring that the disseminated tumor cells are not modified by various means prior to                  
             screening.                                                                                              







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