Ex Parte Austrup et al - Page 7


             Appeal No. 2006-2568                                                              Page 7                
             Application No. 09/744,866                                                                              

             appears to result from a hypertechnical application of legalistic prose relating to that                
             provision of the statute.”  558 F.2d at 1019, 194 USPQ at 196 (emphasis added).  Thus,                  
             we do not agree with the examiner that the failure to exclude modification by “inducing                 
             other defined states” causes claims 24 and 28 to lack written description.                              
                    We also do not agree that the examiner has properly construed claims 24 and                      
             28.  We agree with the examiner that the claim language is somewhat ambiguous.                          
             However, when the claims are given their broadest reasonable interpretation consistent                  
             with the specification, claims 24 and 28 each require that the tumor cells are not                      
             modified – using antibodies, enzymes, lectins, other ligands, other receptors, or                       
             crosslinking reagents – by labeling, attaching particles, triggering aggregation, and/or                
             triggering cluster formation and are not modified by fixing.                                            
                    As properly construed, we do not agree that claims 24 and 28 exclude                             
             disseminated tumor cells that are modified with antibodies in any way.  Thus, we do not                 
             agree with the examiner’s argument that excluding this subject matter causes claims 24                  
             and 28 to lack written description.  Instead, because we have construed claims 24 and                   
             28 consistent with the disclosure at page 13, lines 25-32, we agree with Appellants that                
             the examiner has not shown that this disclosure fails to provide support for the negative               
             limitation of claims 24 and 28.                                                                         














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