Ex Parte Zhong et al - Page 12


            Appeal No. 2006-2826                                                       Page 12              
            Application No. 09/993,907                                                                      

            sentence spanning pages 10-11.  This argument is not persuasive.  Peng clearly                  
            characterizes aminopolycarboxylic acid chelating agents as useful for the chelation of          
            paramagnetic metal ions in magnetic resonance imaging.  Peng, ¶ 50.  This is the same           
            purpose recited in the claims.  Thus, we do not see merit in Appellants’ argument.              
            Accordingly, we find that the Examiner has provided adequate evidence to estsblish              
            prima facie obviousness.  This rejection is affirmed.                                           
            Weissleder in view of Cleary                                                                    
                   Claims 24-27, 32, and 33 stand rejected under 35 U.S.C. § 103(a) as rendered             
            obvious over Weissleder in view of Cleary.8                                                     
                   According to the Examiner, Weissleder discloses a hydrogel-coated medical                
            device, but not a hydrogel that contains substituted or unsubstituted acrylic acid              
            monomers or copolymers of acrylic acid and acrylamide units as required by the claims.          
            Answer, page 5.  This deficiency, the Examiner stated, is remedied by Cleary who                
            teaches these polymers.  Cleary, ¶¶ 13, 14, 68.  The Examiner concluded that utilizing          
            Cleary’s polymers in Weissleder would have been obvious been “[s]uch a modification             
            merely involves the substitution of one known type of hydrogel composition for another.”        
            Answer, page 5.                                                                                 
                   Appellants maintained that the rejection was improper because Cleary disclosed           
            the polymers as useful for medical dressings, not coated medical devices as claimed.            
            Brief, page 11.  They urged that the Examiner did not explain where the suggestion and          
            motivation to combine the references “could be found in the references themselves.”  Id.        


                                                                                                            
            8 Cleary et al. (Cleary), U.S. Pub. Pat. App. No. 2003/0170308 A1, published Sept. 11, 2003.    





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