Ex Parte Reuter et al - Page 8

                Appeal 2006-3319                                                                                 
                Application 10/366,585                                                                           
                                The rejection based on Cohn in view of Bardy                                     
                       Bardy is directed to automated patient care and, in particular, to a                      
                system and method for diagnosing and monitoring the onset, progression,                          
                regression, and status quo of myocardial ischemia using an automated                             
                information collection and analysis patient care system (Bardy ¶¶ 2 and 9).                      
                According to Bardy, preferably, the patient is a recipient of an implantable                     
                medical device, such as a therapeutic device, with a set of leads extending                      
                into the heart and electrodes implanted throughout the cardiopulmonary                           
                system (Bardy ¶ 31).  Examples of information that can be collected include                      
                cardiac injury chemical tests, serum creatinine kinase, serum troponin,                          
                myocardial blood flow, and coronary sinus lactate production (Bardy ¶ 36).                       
                       The Examiner determines it would have been obvious to one of                              
                ordinary skill in the art to use procedures to test for specific chemical                        
                markers and monitor for myocardial ischemia as taught by Bardy in the                            
                method of Cohn (Answer 6-7).  Appellants contend Bardy provides no                               
                suggestion to apply the ischemia detection system in a method for                                
                implanting a mitral valve therapy device and that the Examiner has not                           
                presented any evidence that one having ordinary skill in the art would have                      
                been led to combine a system and method for diagnosing and monitoring                            
                myocardial ischemia for use in automated patient care with a method and                          
                apparatus for reducing myocardial regurgitation (Appeal Br. 11).                                 
                Accordingly, the issue presented is whether it would have been obvious to                        
                combine the teachings of Cohn and Bardy as proposed by the Examiner.                             
                       "Section 103 forbids issuance of a patent when 'the differences                           
                between the subject matter sought to be patented and the prior art are such                      
                that the subject matter as a whole would have been obvious at the time the                       

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