Appeal 2007-0851
Application 10/385,213
silicone polymer” and then cross-linking the silicone polymer “leaving
microsealed compartments filled with hydrophilic solvent--water--and
pharmaceutical throughout the matrix” (id. at col. 2, ll. 61-67). Thus,
Chien’s composition is an aqueous phase emulsion in a silicone matrix.
Powell describes a “silicone emulsion compris[ing] a silicone phase
. . . and an organic phase, comprising an organic liquid,” the organic phase
comprising up to 50 parts by weight (pbw) water per 100 pbw of the organic
phase (Powell, col. 3, ll. 13-28). Powell teaches that the emulsions
preferably contain a discontinuous organic phase in a continuous silicone
phase (id. at col. 3, ll. 29-34). Powell also describes cosmetic compositions
comprising this silicone emulsion and “components, such as . . . hormones,
enzymes, medicinal compounds, anti-microbial agents, anti-fungal agents,
[and] vitamins. . . .” (id. at col. 17, ll. 28-36). In particular, Powell describes
a personal care composition comprising the silicone emulsion “and one or
more water-sensitive dermatological active agents or cosmetic active agents,
such as for example . . . an enzyme” (id. at col. 16, l. 64, to col. 17, l. 1).
We agree with the Examiner that it would have been obvious to
include enzymes, as described in Powell, in the silicone polymer matrix
described in Chien. In particular, based on the teaching in Chien that a
“wide variety of pharmaceuticals may be administered” by its composition
(id. at col. 4, ll. 62-63) and the teaching in Powell that enzymes, as well as
several of the types of compounds specifically described in Chien including
hormones, can be administered in a silicone emulsion (id. at col. 17, ll. 28-
36), we agree that one of ordinary skill in the art would have been motivated
to include enzymes in the silicone matrix described in Chien, and would
8
Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Next
Last modified: September 9, 2013