Ex Parte Fergione et al - Page 12



                  Appeal 2007-1082                                                                                           
                  Application 10/327,383                                                                                     
             1           Curatolo further confirms that the choice of processing approach                                    
             2    depends on the properties sought to be obtained.                                                           
             3           One of those properties is “density” which is a property of interest to                             
             4    appellants.  See Specification, page 48, Table 6 (density and tapped density).                             
             5           Curatolo still further confirms that wet granulation is preferred as a                              
             6    step in making azithromycin tablets.                                                                       
             7           Many of the examples of Curatolo describe products with                                             
             8    azithromycin dihydrate—which, of course, is outside the scope of the claims                                
             9    on appeal.                                                                                                 
           10            However, nothing in Curatolo limits the applicability of the Curatolo                               
           11     invention to azithromycin dihydrate.                                                                       
           12                                                                                                                
           13            E.  Principles of law                                                                               
           14            A claimed invention is not patentable if the subject matter of the                                  
           15     claimed invention would have been obvious to a person having ordinary skill                                
           16     in the art.  35 U.S.C. § 103(a); Graham v. John Deere Co. of Kansas City,                                  
           17     383 U.S. 1 (1966).                                                                                         
           18            Facts relevant to a determination of obviousness include (1) the scope                              
           19     and content of the prior art, (2) any differences between the claimed                                      
           20     invention and the prior art, (3) the level of skill in the art and (4) any                                 
           21     relevant objective evidence of obviousness or non-obviousness.  Graham,                                    
           22     383 U.S. at 17-18.                                                                                         
           23            A person having ordinary skill in the art uses known elements and                                   
           24     process steps for their intended purpose.  Anderson's-Black Rock, Inc. v.                                  
           25     Pavement Salvage Co., 396 U.S. 57 (1969) (radiant-heat burner used for its                                 

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