Ex Parte Yoneda et al - Page 5

                Appeal 2007-1885                                                                                
                Application 11/000,309                                                                          
                the outside wall of the sterile work chamber, and is then carried inside and                    
                through the manipulating means.  The gas that is circulated through the                         
                interior of the manipulating means is discharged to the outside of the                          
                manipulating means through an outlet (22) by a pump or some other suction                       
                device (col. 11, ll. 35-39).  Petersen teaches that the manipulation means can                  
                be a robot (col. 9, ll. 15-31).  Petersen does not disclose the circulation of the              
                gas through the robotic device.                                                                 
                       Suzuki discloses an articulated robot having a hollow arm structure                      
                (3).  An air flow communication passage is maintained within the structure,                     
                so that dust formed in the robot can be discharged outside of a clean                           
                environment in which the robot is operating (col. 1, ll. 34-43).  Suzuki                        
                discloses the pressure level in the robot is controlled and maintained below                    
                the pressure in the clean environment to prevent dust particles from flowing                    
                outside of the robot body (col. 2, ll. 39-49). A first opening covered by a                     
                filter is positioned on the robot structure near a joint or wrist unit.                         
                       The Examiner contends that the teachings of Petersen and Suzuki                          
                suggest the formation of an isolator system comprising a sterile work                           
                chamber in which a robot is placed and has an operating arm for performing                      
                various operations within the sterile work chamber.  The robot comprises a                      
                hollow structure that allows for the circulation of gas that is not in                          
                communication with the sterilized work environment.                                             
                       Appellants contend that the present invention avoids the problem of                      
                corrosion of the inner portion of the robot by sterilizing gas without the need                 
                of covering the outer surface of the robot by supplying a gas from outside of                   
                the sterile work chamber to the interior of the robot to establish a gas                        



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