Ex Parte Seul et al - Page 3

                Appeal 2007-2448                                                                             
                Application 10/192,352                                                                       

                      substrate along at least some of the inscriptions to form a                            
                      plurality of individual biochips with assembled bead arrays                            
                      thereon.                                                                               

                      Thus, claim 2 is directed to a method for producing chips having                       
                biomolecule-bearing beads on their surfaces.  A substrate is first inscribed to              
                form a pattern of chip regions.  Arrays of differently optically encoded                     
                biomolecule-bearing beads are assembled on the patterned substrate.  The                     
                substrate is broken along at least some of the inscriptions to form chips                    
                having bead arrays on them.                                                                  
                2.  PRIOR ART                                                                                
                      The Examiner relies on the following references:                                       
                      Turner  US 5,948,621  Sep. 7, 1999                                                     
                      Goldberg  US 5,959,098  Sep. 28, 1999                                                  
                      Kobylecki  US 6,153,375  Nov. 28, 2000                                                 
                      Anderson  US 6,713,309 B1  Mar. 20, 2004                                               
                      Clerc, P-A et al., Advanced deep reactive ion etching: a versatile tool                
                for microelectromechanical systems, 8 J. Micromech. Microeng. 272-78                         
                (December 1998).                                                                             
                      GLOSSARY OF TERMS USED IN PHYSICAL ORGANIC                                             
                CHEMISTRY, IUPAC Recommendations 1994, T to Z,                                               
                http://www.chem.qmul.ac.uk/iupac/gtpoc/TtZ.html.                                             
                3.  ANTICIPATION                                                                             
                      Claims 2 and 26-29 stand rejected under 35 U.S.C. § 102(e) as                          
                anticipated by Kobylecki (Answer 3-6).1                                                      

                                                                                                            
                1 The Examiner also relied on the “GLOSSARY OF TERMS USED IN                                 
                PHYSICAL ORGANIC CHEMISTRY, IUPAC Recommendations 1994” to                                   
                                                     3                                                       

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