Ex Parte Lal et al - Page 7

                  Appeal 2007-2517                                                                                         
                  Application 10/311,196                                                                                   
                         In sum, the record lacks evidence to support Appellants’ position.                                
                  Counsel’s argument cannot take the place of evidence lacking in the record.                              
                  Estee Lauder Inc. v. L’Oreal, S.A., 129 F.3d 588, 595, 44 USPQ2d 1610,                                   
                  1615 (Fed. Cir. 1997).  Because the Examiner has set forth a reasonable                                  
                  doubt as to why an explicit utility has not been disclosed as of the filing                              
                  date, the burden shifted to Appellants to provide rebuttal evidence.  See In re                          
                  Brana, 51 F.3d 1560, 1567, 34 USPQ2d 1436, 1441 (Fed. Cir. 1995).                                        
                  Outside of argument of counsel, Appellants’ have supplied no objective                                   
                  evidence that the only reasonable interpretation of the data in Table 2 is that                          
                  the SEQ ID NO: 2 has taste-specific receptor activity.                                                   

                  Post-filing evidence                                                                                     
                         Appellants’ provide Li – published subsequent to the filing of the                                
                  instant application – which they state confirms the asserted utility of SEQ ID                           
                  NO: 2 as a human taste-specific receptor (Br. 8).  Appellants’ contend that                              
                  “[a]s is well appreciated, post-filing evidence may be used to substantiate an                           
                  asserted utility” (Br. 8), but provide no authority upon which this assertion is                         
                  based.                                                                                                   
                         It is true that post-filing evidence can be relied on for certain                                 
                  purposes. A later dated publication can be used as evidence of the level of                              
                  ordinary skill in the art at the time of the application, as evidence that the                           
                  disclosed device would have been operative, and of the state of the art                                  
                  existing on the filing date of an application.  See Gould v. Quigg, 822 F.2d                             
                  1074, 1078, 3 USPQ2d 1302, 1305 (Fed. Cir. 1987); In re Hogan, 559 F.2d                                  
                  595, 605, 194 USPQ 527, 537 (CCPA 1977).  However, post-filing evidence                                  
                  can not be used to demonstrate that the Specification, as filed, sets forth a                            

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