Ex parte SECOR et al. - Page 8




          Appeal No. 94-1709                                                          
          Application 07/716,115                                                      


               In the preceding paragraphs, I have attempted to                       
               outline the status of the potato mesophyll                             
               protoplast/ plant regeneration experimental system                     
               as it pertains to the improvement of this                              
               significant crop plant.  The results are                               
               preliminary, and it will require an additional 2 or                    
               more years before we can truly assess the                              
               horticultural worth of regenerated material.                           
               Biologically and genetically, however, certain                         
               misgivings about the utility of such systems appear                    
               satisfied.  [Shepard, page 214, emphasis added.]                       
               All in all, we believe that the examiner "stretches" the               
          teaching of Shepard by stating as follows:                                  
               Shepard teaches that protoplasts can be subjected to                   
               suspected disease causing agents during development                    
               and subsequently resistant strains can be selected                     
               from the wild type by their lack of disease                            
               symptoms, i.e.[,] their lack of susceptibility to                      
               the causative agent of the disease.  [Examiner's                       
               Answer, paragraph bridging pages 3 and 4.]                             
          Shepard is more circumspect than that.  Shepard describes                   
          "prospects for protoplast and/or callus selection," but the                 
          results are preliminary in nature.  According to Shepard,                   
          "[t]he results are preliminary, and it will require an                      
          additional 2 or more years before we can truly assess the                   
          horticultural worth of regenerated material" (Shepard, page                 
          214).  Although it is reasonable to expect that some variants               
          could be selected early as either protoplasts or small calli                
          and then be regenerated into plants possessing a predicted                  

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