Ex parte KEENAN - Page 7




                 Appeal No. 97-2833                                                                                                                     
                 Application 08/236,190                                                                                                                 


                 Claims 34, 35, 37-39, 41-46, 48-50, 52-57, 59-61, 63-66 are rejected under the                                                         
                 judicially created doctrine of obviousness-type double patenting over claims 1-11 of                                                   
                 Keenan ‘928.3                                                                                                                          
                          Appellant’s independent claim 34 differs from claim 1 of Keenan ‘928 in that 1)                                               
                 appellant’s claim 34 recites administering one or more nicotine metabolites or their                                                   
                 pharmaceutically acceptable salts whereas claim 1 of Keenan ‘928 recites                                                               
                 administering cotinine or a pharmaceutical acceptable salt thereof, 2) in appellants’                                                  
                 claim 34, administering 1-100 mg/kg of body weight of nicotine metabolites or their                                                    
                 pharmaceutically acceptable salts in the free base form is recited, but the amount of                                                  
                 cotinine or a pharmaceutical acceptable salt thereof is not recited in claim 1 of Keenan                                               
                 ‘928, and 3) appellant’s claim 34 is directed toward managing short term human body                                                    
                 weight changes whereas claim 1 of Keenan ‘928 is directed toward control of long term                                                  
                 human body weight.  Appellant’s independent claims 45 and 56 differ from claim 1 of                                                    
                 Keenan ‘928 only in the first and second respects noted above.                                                                         
                          Because cotinine is a nicotine metabolite, the recitation in claim 1 of Keenan                                                
                 ‘928 of administering cotinine is a disclosure of administering a nicotine metabolite.                                                 
                 Regarding the amount of cotinine administered in claim 1 of Keenan ‘928, it is proper to                                               




                          3No new ground of rejection is applied to claims 82, 83, 85 and 87-91.                                                        
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