Ex parte BONAVENTURA et al. - Page 6




          Appeal No. 95-1779                                                          
          Application 07/683,130                                                      
          of the coating.  Finally, Christie states on page 3 of the                  
          full text of his article (of record and attached hereto):                   
               Enzyme systems which are capable of attacking the                      
               proteinaceous adhesives produced by fouling organisms                  
               have been suggested but are unlikely to be developed due               
               to cost and to practicability under service conditions.                
          2.   Section 103 in view of Christensen or Hatcher and Trevan               
               Christensen and Hatcher describe processes for preventing              
          fouling of marine surfaces which comprise adding an enzyme                  
          to industrial waters (Christensen, col. 1, l. 30-43; Hatcher,               
          col. 1, l. 64, to col. 2, l. 9).  According to the examiner                 
          (Ans., p. 6), “[t]he instant claims differ by reciting that                 
          the enzyme is immobilized to the surface of the structure                   
          exposed to the environment . . . .”  The examiner adds (Ans.,               
          p. 6),                                                                      
          “Trevan discloses that it is conventional in the art to                     
          immobilize enzymes so as to render them more stable and allow               
          them to be easily recovered and/or re-used (See page 66).”                  


               In view of the combined teaching, the examiner concludes               
          (Ans., pp. 6-7, bridging para.):                                            
               [I]t would have been obvious to one of ordinary skill in               
               the art to immobilize the enzymes of Christensen . . . or              
               Hatcher . . . on the surfaces of the process equipment as              
               suggested by Trevan for the known and expected advantages              
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