Ex parte IBRAHIM et al. - Page 2




             Appeal No. 95-4321                                                                                       
             Application 07/976,241                                                                                   


                    hydrolyzing the lactose permeate to make a lactose hydrolysate comprised of D-                    
             galactose and glucose;                                                                                   
                    subjecting the lactose hydrolysate to fermentation conditions whereby the glucose is              
             selectively fermented to ethanol;                                                                        
                    separating the D-galactose from the ethanol, making a solution having a                           
             concentration of from about 10% to about 60% by weight D-galactose;                                      
                    subjecting the solution of D-galactose to enzymatic isomerization with L-arabinose                
             isomerase at an isomerization pH from about 5.5 to about 7.0 and a temperature from                      
             about 50EC to about 70EC; and                                                                            
                    wherein the yield of D-tagatose is from about 20% to about 45% by weight based                    
             on D-galactose.                                                                                          
                    11.  A method of producing D-tagatose comprising enzymatic isomerization of D-                    
             galactose with L-arabinose isomerase at an isomerization pH from about 5.5 to about 7.0                  
             and a temperature from about 50EC to about 70EC, wherein the D-galactose is in a                         
             solution having a concentration of from about 10% to about 60% by weight D-galactose                     
             and the yield of D-tagatose is from about 20% to about 45% by weight based on D-                         
             galactose.                                                                                               
                             2                                                                                        
             The references  relied upon by the examiner are:                                                         
             Beadle et al. (Beadle)             5,002,612            Mar.  26, 1991                                   
             Barker et al. (Barker)                         4,069,104       Jan.  17, 1978                            
             Fiehring et al. Chemical Abstracts, Volume 73(25), p129742e (1970)                                       


                    2The examiner has relied upon two abstracts from Chemical  Abstracts in support of the conclusion 
             of obviousness.  A patentability determination under 35 U.S.C. § 103 is fact specific.  Almost by definition
             the full text document which is abstracted is more fact rich than the abstract.  We strongly urge the    
             examiner to premise his patentability determinations in the future, upon the most fact rich record which can
             reasonably be developed.  It is the experience of the board that review of the full text document when a 
             rejection is premised upon an abstract will most likely significantly strengthen or weaken the examiner's
             position.  Rarely does consideration of the full text document leave one in the same position where one was
             after considering the abstract alone.  Here, we have considered the abstracted German document and the   
             translation thereof.                                                                                     
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