Ex parte EICHENAUER et al. - Page 8




                 Appeal No. 96-1795                                                                                                                     
                 Application No. 08/262,745                                                                                                             


                 Eichenauer I or II and thus has not established a prima facie                                                                          
                 case of obviousness (Brief, pages 9-11).                                                                                               
                          “[T]he examiner bears the initial burden, on review of                                                                        
                 the prior art ..., of presenting a prima facie case of                                                                                 
                 unpatentability.”  In re Oetiker, 977 F.2d 1443, 1445, 24                                                                              
                 USPQ2d 1443, 1444 (Fed. Cir. 1992).  However, we disagree with                                                                         
                 appellants’ argument since the examiner has provided reasoning                                                                         
                 sufficient to establish a prima facie case of obviousness (see                                                                         
                 the Answer, page 8).   When the ranges of the prior art and3                                                                                                  
                 the claims on appeal are so close, one of ordinary skill in                                                                            
                 the art would have the expectation of similar properties in                                                                            
                 the absence of any showing of unexpected results.  In re                                                                               
                 Geisler, 116 F.3d 1465, 1469-70, 43 USPQ2d 1362, 1365 (Fed.                                                                            
                 Cir. 1997); In re Woodruff, 919 F.2d 1575, 1578, 16 USPQ2d                                                                             
                 1934, 1936 (Fed. Cir. 1990); Titanium Metals Corp. v. Banner,                                                                          
                 778 F.2d 775, 783, 227 USPQ 773, 779 (Fed. Cir. 1985).  It is                                                                          



                          3It should also be noted that molecular weight                                                                                
                 determination is not exact, as shown by appellants’ examples                                                                           
                 (see the specification, page 20, line 13, "ca. 51,000") and                                                                            
                 the examples in Eichenauer I or II (e.g., see Eichenauer I,                                                                            
                 column 6, lines 16, 25, 30, and 35, "approx.").                                                                                        
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