Appeal No. 1997-3811 Page 3
Application No. 08/357,845
and said first liquid phase, to elute said (+)
enantiomer and said (-) enantiomer from said
countercurrent chromatographic centrifuge column,
wherein said quantity is from 1 mg to 1 kg.
In addition to alleged admitted prior art1, the prior art
references of record relied upon by the examiner in rejecting
the appealed claims are:
Pirkle et al. (Pirkle ‘293) 5,256,293 Oct. 26, 1993
Pirkle et al. (Pirkle ‘440) 5,290,440 Mar. 01, 1994
Cahnmann et al., “Synthesis and characterization of
N-bromoacetyl-3,3',5-triiodo-L-thyronine,” Journal
of Chromatography Vol. 538 (1991), pages 165-175
(Cahnmann).
Pirkle, “Chiral stationary phase design Use of
intercalative effects to enhance
enantioselectivity,” Journal of Chromatography Vol.
641 (1993), pages 11-19 (Pirkle article).
Claims 1-7 stand rejected under 35 U.S.C. § 102 as being
anticipated by or, in the alternative, under 35 U.S.C. § 103
as being unpatentable over Pirkle ‘440. Claims 1-7 stand
1 See specification at pages 1-5, page 8, lines 22-28 and
page 17, last paragraph.
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