Ex parte MA et al. - Page 9




          Appeal No. 1997-3811                                        Page 9          
          Application No. 08/357,845                                                  

          not established with reasonable certitude that the reference                
          to countercurrent chromatographic devices in each of the                    
          applied Pirkle patents coupled with the particular description              
          of enantiomer separation processes using other specified                    
          separation equipment in those patents necessarily constitutes               
          a description of appellants’ process including the combination              
          of steps recited in appealed claim 1.  In particular, the                   
          examiner has not shown that either applied Pirkle patent                    
          necessarily describes a separation method that includes the                 
          addition of a chiral selector to a first liquid phase that is               
          charged to a countercurrent centrifuge column, the                          
          introduction of a racemic mixture into the column and the                   
          passage of a second liquid phase through the so charged column              
          to elute enantiomers therefrom.  Hence, the examiner has                    
          simply not carried the initial burden of establishing a prima               
          facie case of anticipation as to the appealed claims.                       
          Consequently, we reverse the rejections under 35 U.S.C. § 102.              
                                                                                     




                          Rejections under 35 U.S.C. § 103                            







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