Ex Parte KRUTZIK - Page 8




              Appeal No. 1999-1423                                                                                      
              Application 08/261,639                                                                                    



                     In view of the above, we find the examiner has failed to established a prima facie                 
              case of obviousness, and the rejection of claims 48, and 50-60 under 35 U.S.C. § 103                      
              over Tzeng and Berry is reversed.                                                                         


              35 U.S.C. § 103                                                                                           
                     The rejections of claims 48 and 49 under 35 U.S.C. § 103 over Tzeng and Berry                      
              in further view of admissions in the specification; of claims 48 and 57 under 35 U.S.C. §                 
              103 over Tzeng and Berry in further view of Weng; and of claims 48, 59 and 61  under                      
              35 U.S.C. § 103 over Tzeng and Berry in further view of Kondo are also reversed.                          
                     All of these additional rejections rely on the primary combination of references,                  
              Tzeng and Berry.  The examiner relies on admissions in the specification to establish                     
              that the use of albumin, and variations on it, were known in the art and were readily                     
              available from commercial suppliers.   Answer, page 6.  Weng is relied on by the                          
              examiner for the disclosure of poly(vinyl) butyrate support material.  Id.   Kondo is relied              
              on for the disclosure of the use of a prefilter device in immunoassays.  Answer, page 7.                  
                     The additional cited references fail to overcome the deficiencies of the primary                   
              combination of Tzeng and Berry and the failure to describe specific glycoproteins                         
              selected from the group consisting of HIV-1 glycoprotein 41 and HIV-2 glycoprotein 36.                    




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