NICHOLS et al. V. TABAKOFF et al. - Page 15




               Interference No. 104,522 Paper108                                                                                                 
               Nichols v. Tabakoff Page 15                                                                                                       
                        A. Yes.                                                                                                                  
                        Q. That's in your writing, too?                                                                                          
                        A. Yes.                                                                                                                  
                        Q. Same with the eleven quats: Need only six; is that right?                                                             
                        A. Yes.                                                                                                                  
                        [NR, p. 90, 1. 22 - p. 91,1. 6.]                                                                                         
                                                 I. analysis of evidence                                                                         
                        Notebook Ex 2030 may well show reactions and products that Dr. Nichols                                                   
               desired and theoretically expected to occur. However, Ex 2030, taken alone, is                                                    
               insufficient to establish that the predicted reactions and theoretically expected products                                        
               did in fact occur. NIVIR scan Ex 2031 is of no probative value because it is neither                                              
               authenticated nor explained. Moreover, Dr. Nichols testified that one could not tell the                                          
               structure of a compound from its NIVIR spectrum alone. No other spectral data (e.g.,                                              
               mass spectral or "much more sophisticated NMR" data), etc., have been offered for                                                 
               compound 94A-64-11. Thus, Nichols' alleged synthesis of (NN-diethyl)-4-ureido-5,7                                                 
               dichloro-2-carboxy-quinoline methyl ester) rests on the uncorroborated testimony of Dr.                                           
               Nichols. To prove reduction to practice by inventor testimony, the inventor's testimony                                           
               must be corroborated by independent evidence. Slip-Trac , 304 F.3d at 1265, 64                                                    
               USPQ2d at 1429; Coope , 154 F.3d at 1330, 47 USPQ2d at 1903.                                                                      
                        In addition, while an inventor need not know that his invention will work for                                            
               conception to be complete, the discovery that it actually works is part of its reduction to                                       
               practice. Burrouclhs Wellcome Co. v. Barr Lab., 40 F.3d 1223, 1228, 32 USPQ2d                                                     
               1915, 1919 (Fed. Cir. 1994). Here, Nichols has not met its burden of showing that                                                 
               compound 94A-64-11 would work for its intended purpose. No anticonvulsant or other                                                
               pharmacological activity testing has been offered for compound 94A-64-11. Simply                                                  







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