Appeal No. 2005-2663 Page 3
Application No. 10/140,323
Figures 1B and 1C are, respectively, the “adjacency list” and “accessibility list” of
the genetic network of Figure 1A. An adjacency list (abbreviated Adj) is a list of genes
whose activities directly influence each other; “[o]ne might also call it the list of direct
regulatory interactions. It completely defines the structure of the network.”
Specification, page 11. An accessibility list (abbreviated Acc) “shows all nodes (genes)
that can be accessed (influenced in their activity state) from a given node by following
paths of direct interactions. In the context of a genetic network, one might also call it
the list of perturbation effects or the list of regulatory effects.” Id.
Figures 1B and 1C are reproduced below:
Figure 1B is a list of the genes in the network and the genes that each of them
directly affects. Figure 1C is a list of the genes in the network and the genes that each
of them directly or indirectly affects. Thus, for example, Figure 1A shows that gene 14
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