Ex Parte Wagner - Page 10


              Appeal No. 2005-2663                                                              Page 10                
              Application No. 10/140,323                                                                               

                     Regarding claim 20, the examiner argues that the specification does not describe                  
              the limitation “biotic and abiotic environmental stress”.  It is true that the specification             
              does not contain this phrase, in those words.  The specification does, however, refer to                 
              “different environmental conditions” generally, as well as recite examples of both biotic                
              and abiotic stresses.3  See pages 3-4:  the claimed method can “reconstruct networks                     
              of gene interactions that change in different environmental conditions,” “identify                       
              pathways for host defense in plants,” “identify gene pathways in plants responsible for                  
              insecticidal activity,” and “identify pathways in plants that are responsible for drought                
              tolerance and virulence.”  See also page 35:  the “invention will answer a multitude of                  
              questions about the genetic architecture of organisms such as . . . in different                         
              environmental conditions.”                                                                               
                     We agree with Appellant that the examiner has not adequately explained why                        
              these specific and generic descriptions are inadequate to show possession of the                         
              method of claim 20 to a person of ordinary skill in the art.  We therefore reverse the                   
              rejection for lack of adequate written description (new matter).                                         
              3.  Obviousness                                                                                          
                     The examiner rejected claims 1-4, 9, 16, 17, 19, and 20 under 35 U.S.C. § 102(a)                  
              as anticipated by Küffner.4  The examiner’s reasoning with respect to claim 1 is as                      
              follows:                                                                                                 
                     Kuffner et al. disclose a method and system, PETRI nets, for representing                         
                     differential content of individual databases (KEGG and BRENDA pathway                             
                     databases), comparing genomic and network information; and defining                               
                                                                                                                       
              3 A biotic stress is one that is “caused or produced by living things,” and an abiotic stress is one “not
              biotic”; i.e., not caused by living things.  Merriam-Webster’s Collegiate Dictionary, Deluxe Edition (1998).
              4 Küffner et al., “Pathway analysis in metabolic databases via differential metabolic display (DMD),”    
              Bioinformatics, Vol. 16, pp. 825-836 (2000).                                                             





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