Ex Parte Conroy et al - Page 5

                Appeal 2006-3259                                                                             
                Application 09/785,188                                                                       

                      Claim 24.1  The sol [according to claim 15, wherein: said hydroxy                      
                      metallate is formed by hydrolysis of a sol-gel precursor], further                     
                      comprising an organic solvent comprising an organic by-product                         
                      arising from the hydrolysis of said sol-gel precursor.                                 

                                           ISSUE ON APPEAL                                                   
                Claim 26                                                                                     
                      The Examiner contends the “method of claim 26 [is] the same as the                     
                method . . . disclosed by Uo et al except that the claim[] require[s] a                      
                vegetative cell instead of yeast spores.”  Answer 5.   The Examiner further                  
                contends Hino cures this deficiency:  “It would have been obvious to use                     
                vegetative yeast cells in place of the yeast spores in the method of Uo et al                
                as suggested by Hino . . . .  Using vegetative cells not in spore form would                 
                have been expected to be advantageous due to simplification resulting from                   
                not having to convert vegetative cells to spores and then covert the spores to               
                vegetative cells to provide the cells in active form for use.”  Answer 5-6.                  
                      Appellants contend there would have been no motivation to combine                      
                Uo and Hino because “one of ordinary skill would expect Uo’s gelation                        
                solution [containing methanol] to be toxic to Hino’s vegetative cells and thus               
                would not have a reasonable expectation of success with the combination.”                    
                Br. 4.  Appellants rely on a “technical understanding of the antimicrobial                   
                activity of alcohols” and on Uo’s and Hino’s teachings for support.  Br. 5                   
                (citing DISINFECTION, STERILIZATION, AND PRESERVATION, Ch. 12                                
                (“Alcohols”) (Seymour Block ed.) (5th ed. 2001)).                                            

                                                                                                            
                1 Claim 24 is dependent upon claim 17; claim 17 is dependent upon claim                      
                15.                                                                                          
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