Ex Parte Conroy et al - Page 11

                Appeal 2006-3259                                                                             
                Application 09/785,188                                                                       

                Appellants’ reasoning.  Further, given that the skilled artisan can use                      
                bacterial spores to practice the invention of claim 28, there’s even stronger                
                motivation to employ the teachings of Uo.  See Answer 14.  Appellants’                       
                remaining arguments with respect to claim 28 mirror those made with                          
                respect to claim 26 and have been addressed above.                                           
                Claim 15                                                                                     
                      The Examiner relies on Uo, Hino, Kline and Rao to reject claim 15                      
                under § 103(a).  Claim 15 is to a sol comprising P moles of a hydroxy                        
                metallate, W moles of water, a dispersant, and a “biological material,” which                
                can be yeast spores, “wherein a ratio of W:P is greater than 25:1.”  The                     
                additional disputed limitation with respect to claim 15 is the W:P ratio.                    
                Br. 15.  The Examiner relies upon Klein, a reference that shows a sol                        
                solution with a ratio of 32:1, and Rao, a reference that discloses “the                      
                influence ratios of precursor, catalyst, solvent and water [have] on properties              
                of silica aerogels.”  Answer 7-8, 16.                                                        
                      Appellants respond that a ratio of 32:1 in Klein yields 65% ethanol, an                
                amount Block shows is “effective at killing a number of bacterial species in                 
                under one minute.”  Br. 15-16 (emphasis Appellants’).  The Examiner                          
                responds that the “biological material” of claim 15 would include the                        
                durable yeast spores taught by Uo.  Answer 15.  Further, according to the                    
                Examiner, for the reasons given relating to claim 26, the skilled artisan                    
                would have been motivated to reduce the alcohol level, if needed to preserve                 
                the activity of the cells.  Answer 16.  Finally, Block does not disclose the                 
                impact of alcohol on cells in a sol-gel process.  Answer 11.  Thus, the value                



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