Ex Parte Jacobs et al - Page 9

              Appeal 2007-0539                                                                     
              Application 10/264,026                                                               

              Appellants to establish that the prior art pseudopterosin compositions do not        
              contain pseudopterosin compounds obtainable from Symbiodinium spp., or               
              that the prior art compositions contain animal impurities.                           
                    Appellants point to Figures 1 and 2 of the Specification, thin layer           
              chromatograms which show “the separations for the algal fraction                     
              (Symbiodinium spp. symbiont) and the coral (animal) fraction[,]” as                  
              evidence that the two fractions “are clearly different” (Br. 2-3).  We do not        
              disagree, but Appellants have not explained how the fact that crude coral and        
              algal extracts are different has any bearing on whether the pseudopterosin           
              compositions of the cited prior art contain animal impurities.  Therefore, this      
              evidence does not persuade us that the claimed compositions are not                  
              anticipated by the prior art compositions.                                           
                    Appellants additionally rely on two “HPLC chromatographs of an                 
              extract from Symbiodinium spp. (algae) (Figure A) and an extract of                  
              Pseudopterogorgia elisabethae (coral) (Figure B)”9 (Br. 6), as evidence that         
              “the algae composition/extract contains different compounds as well as               
              having different concentrations of the pseudopterosin compounds when                 
              compared to the coral composition/extract as evidenced by the difference in          
              the peaks” (id. at 7).  Appellants argue that “the algae extract clearly has         
              many other compounds as indicated by the numerous peaks not observed                 
              from the coral extract.  Since the algae extract is from a non-animal origin,        
              these additional compounds in the algae extract are not animal impurities,           

                                                                                                  
              9  These two chromatographs were originally submitted with Appellants’               
              Amendment-After-Final on June 17, 2004, and are reproduced on pages 6                
              and 7 of the Brief.                                                                  
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