Appeal 2007-1132
Application 10/036,999
Claim 7:
Claim 7 is drawn to a method that requires four steps. Step (a)
requires that prior to scanning an interrogating light across an array package,
the interrogating light power is calibrated against a control signal
characteristic from a light system which provides the interrogating light of a
power which varies in response to the control signal characteristic. Step (b)
follows step (a) and requires that an interrogating light be scanned across
multiple sites on an array package comprising an addressable array of
multiple biopolymeric features of different moieties. According to step (b),
the scanned sites comprise multiple features of the array. Step (c) requires
that the signals from respective scanned sites that are emitted in response to
the interrogating light are detected. Step (d) requires that the interrogating
light power is altered for a first site on the array package during the array
scanning using the calibration of step (a), based on either (i) the location of
the first site or (ii) a determination that the emitted signal from the first site
will be outside a predetermined range absent the alteration. In addition, step
(d) requires that the interrogating light power is altered during a row scan of
the interrogating light. We interpret this last clause of step (d) to require that
the interrogating light power is altered while the row scan is being
performed.
The Examiner finds that
Bengtsson teaches a method comprising: calibrating an
interrogating light power versus a control signal characteristic
from a light system which provides the interrogating light of a
power which varies in response to the control signal
characteristic; scanning an interrogating light across multiple
sites on an array package which scanned sites include multiple
features of the array; detecting signals from respective scanned
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