Appeal No. 95-0976 Application No. 07/936,558 a product claim which is broader than the single compound whose antimycotic activity is exhibited in the specification. Assuming arguendo that the examiner had established a prima facie case to reject this claim, the examiner fails to adequately rebut the position taken by appellants. The data presented in the specification on pages 25-29 exhibits antibiotic activity in vivo against one strain of yeast and against Pneumocystis carinii. However the antibiotic activity of one of the claimed compounds against several strains are shown in vitro in this section of the specification. Having shown by animal testing the effectiveness of a compound which exhibited antibiotic properties both in vitro and in vivo, the appellants' position is that an adequate correlation between in vitro test data and in vivo test data has been established. The examiner reiterates that one example is inadequate to support many but does not give any reasons why the correlation between in vitro and in vivo has not been established by the data submitted in the specification. 10Page: Previous 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 NextLast modified: November 3, 2007