Ex parte BOUFFARD et al. - Page 15




          Appeal No. 95-0976                                                          
          Application No. 07/936,558                                                  


               Appellants argue that the requirement of the claimed                   
          compounds and compositions with respect to the propanolamine                
          substituent at the Thr position is neither taught nor                       
          suggested by the applied art.  We agree with appellants in                  
          this regard.  This position being dispositive of the issue of               
          obviousness for each of the claims we will not reach the other              
          questions raised by appellants.  We note in particular the                  
          issue as to the claimed R  position desmethyl variations (set5                                                  
          forth in claims 2-12 herein) and point out that the                         
          Supplemental Examiner's Answer (Paper #17) refers to                        
          variations of echinocandins obtained from a particular                      
          microbial source.  However, appellants did not file any Reply               
          Brief to address this reasoning.  We take no position on this               
          specific matter.                                                            
               The examiner bears an initial burden of establishing that              
          one of ordinary skill in the art would have found the claimed               
          invention to have been obvious at the time that it was made.                
          The evidence relied upon must support such a conclusion.  As                
          was set forth in In re Vaeck, 947 F.2d 488, 493, 20 USPQ2d                  
          1438, 1442 (Fed. Cir. 1991):                                                
                    Where claimed subject matter has been rejected                    
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