Ex parte MARTIS et al. - Page 6




          Appeal No. 95-2970                                                          
          Application No. 07/995,106                                                  


               order to optimize the ultrafiltration profile, thus                    
               arriving at substantially the molecular weight range                   
               recited in the instant claims.  [Examiner's Answer,                    
               page 4, first full paragraph].                                         
          Simply stated, the foregoing is an example of ipse dixit                    
          reasoning.  On this record, it is the appellants'                           
          specification, not Klein's disclosure, which provides the                   
          guidelines and direction leading to a polypeptide mixture                   
          having the specific molecular weight characteristics recited                
          in independent claim 10.  The examiner's conclusion of                      
          obviousness is not supported by an adequate factual                         
          foundation, and cannot stand.  This rejection is reversed.                  
               Claims 21 through 27 depend directly or indirectly from                
          claim 10 and, therefore, include the limitations pertaining to              
          molecular weight recited therein.  Again, the examiner has not              
          established that the Klein reference is sufficient to support               
          a conclusion of obviousness of claims containing those                      
          limitations.  Nor does the Steudle reference cure that                      
          deficiency in Klein.  Accordingly, the rejection of claims 21               
          through 27 under 35 U.S.C. § 103 as unpatentable over the                   
          combined disclosures of Klein and Steudle is reversed.                      



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