Ex parte MARTIS et al. - Page 7




          Appeal No. 95-2970                                                          
          Application No. 07/995,106                                                  


               In setting forth the statement of rejection of claims 1                
          through 9, 21 through 27, and 35 through 43 under 35 U.S.C.                 
          § 103 as unpatentable over the combined disclosures of Klein                
          and Steudle (Examiner's Answer, pages 4 and 5), the examiner                
          does not refer to independent claim 41.  Rather, the examiner               
          discusses claim 41 in the context of the § 103 rejection of                 
          claims 10 through 20 over Klein.  See the Examiner's Answer,                
          paragraph bridging pages 3 and 4.  This is, to say the least,               
          unorthodox.  In any event, we have carefully reviewed the                   
          Klein reference, including column 6, TABLE 1, referenced by                 
          the examiner, but find that the amino acid composition there                
          set forth bears little relationship to the amino acid                       
          composition recited in claim 41.  On this record, the examiner              
          has not established how a person having ordinary skill would                
          have been led from "here to there," i.e., from the amino acid               
          composition disclosed by Klein in column 6, TABLE 1, to a                   
          polypeptide having the amino acid composition recited in claim              
          41.  The examiner has not established a prima facie case of                 
          obviousness of independent claim 41 or the claims depending                 
          directly or indirectly therefrom (claims 42 and 43).                        


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