Ex parte MARTIS et al. - Page 11




                 Appeal No. 95-2970                                                                                                                     
                 Application No. 07/995,106                                                                                                             


                 similarities between the claimed polypeptide composition and                                                                           
                 the polypeptide composition disclosed by Klein.  The examiner                                                                          
                 should weigh the significance of such similarities as:  (1)                                                                            
                 the source of the two polypeptides appear to be the same,                                                                              
                 compare Klein at column 5, line 24 through column 6, line 23,                                                                          
                 with appellants' specification, pages 9-10; (2) the disclosed                                                                          
                 utility is the same;  and (3) the parameters of molecular                                                                              
                 weight, although not identical, appear to be closely related.                                                                          
                 We are mindful that, in the specification, appellant suggests                                                                          
                 that the molecular weight in claim 10 is critical or gives                                                                             
                 rise to unexpected results.  Yet the specification contains no                                                                         
                 specific comparison of the claim designated polypeptide                                                                                
                 mixture, without dextrose, with the closest prior art mixture                                                                          
                 disclosed by Klein.  Taking into consideration these                                                                                   
                 similarities, the examiner should re-evaluate patentability of                                                                         
                 claim 10 in light of Kline.   In so doing, the examiner should3                                                                                     
                 consider the claimed subject matter as compared to Klein in                                                                            
                 light of the legal principles discussed in such cases as: In                                                                           
                 re Geisler, 116 F.3d 1465, 43 USPQ2d 1362 (Fed. Cir. 1997); In                                                                         

                          3These points were not relied upon or addressed by the                                                                        
                 examiner in this appeal.                                                                                                               
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