Ex parte THIRUVENGADAM et al. - Page 12




          Appeal No. 1996-2308                                                        
          Application 08/179,008                                                      







               A and D are independently a bond; C -C  cycloalkylene; C -3  6                1               
          C  alkylene; C -C  alkenylene; C -C  alkynylene; and alkylene,10           1  10             1 10                                        
          alkenylene or alkynylene chain as defined substituted by one                
          or more substituents independently selected from the group                  
          consisting of phenyl, W-substituted phenyl, heteroaryl and W-               
          substituted heteroaryl, wherein heteroaryl is as defined                    
          above; an alkylene, alkenylene or alkynylene chain as defined               
          interrupted by one or more groups independently selected from               
          the group consisting of -O-, -S-, -SO-, -SO -, -NR , -C(O)-,2      8                         
          C -C cycloalkylene, phenylene, W-substituted phenylene,                     
           3 6                                                                        
          heteroarylene and W-substituted heteroarylene; or an                        
          interrupted alkylene, alkenylene or alkynylene chain as                     
          defined substituted by one or more substituents independently               
          selected from the group consisting of phenyl, W-substituted                 
          phenyl, heteroaryl and W-substituted                 heteroaryl;            
          of R -D is selected from the group2                                                 consisting             
          of halogeno, OH, lower alkoxy, -                     OC(O)R , -6                
          NR R , -SH and -S(lower alkyl);45                                                                        
               R  is 1-3 groups independently selected from the group3                                                                     
          consisting of lower alkyl, lower alkoxy, -COOH, NO , -NR R , OH2     4 5                 
          or halogeno;                                                                
                4     5                                                               
               R  and R  are independently selected from H and lower                  
          alkyl;                                                                      
                6                       3                    3                      
               R  is lower alkyl, phenyl, R -phenyl, benzyl of R -benzyl;             
                                             R  is OH, lower alkyl,7                                       
                                                         3          3                 
                                        phenyl, benzyl, R -phenyl or R -              
                                        benzyl;                                       
                                                                                     
                                                                                     
               R  is H, OH, alkoxy, phenoxy, benzyloxy,8                                                                     
                84 5                                                                  
                                           3                                         
               -NR R , lower alkyl, phenyl or R -phenyl;                              

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