Ex parte WONG et al. - Page 7





                   Appeal No. 1996-1959                                                                                                
                   Application No. 07/946,546                                                                                          

                           the 4-position hydroxyl is up rather than down, where as in mannose, the 2-                                 
                           position hydroxyl is up rather than down, with all of the other hydroxyls                                   
                           maintaining the their same configurations relative to the plane of the                                      
                           ring…..by using ring structural formulas, workers of less than ordinary skill in                            
                           the art can know the identity of a sugar, and one can identify a single sugar                               
                           from among the 32 possible optical and anomeric isomers for a given                                         
                           C6H12O6 sugar.                                                                                              
                   Appellants argue that the compound taught by Schreiner and Schrell differs from the                                 
                   compound of claim 6 with respect to the position of the substituent at a number of                                  
                   carbon atoms on the ring.  According to the Appellants, just as glucose is different                                
                   from galactose and mannose (by virtue of the positioning of the hydroxyl                                            
                   substituents), so too is the claimed compound different from that taught by the cited                               
                   art.                                                                                                                
                           The Examiner does not come to grips with Appellants’ argument, either in the                                
                   Answer or in the Supplemental Answer.  Rather, the Examiner steadfastly maintains                                   
                   her position that the compound of the claim and that of the prior art are the same.                                 
                   The Examiner appears to ignore Appellants’ exhibits, documenting conventional                                       
                   numbering and nomenclature for carbohydrates (sugars, in particular).  In the face of                               
                   Appellants’ detailed comparison between the claimed compound and the prior art                                      
                   compound, including a discussion on the fundamentals of carbohydrate structure                                      
                   and nomenclature, we find that the Examiner’s position is untenable.                                                




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