Ex parte NATHMAN et al. - Page 5




          Appeal No. 1997-1577                                       Page 5           
          Application No. 07/941,466                                                  


          references to arrive at the claimed invention.  Such reason                 
          must stem from some teaching, suggestion or implication in the              
          prior art as a whole or knowledge generally available to one                
          having ordinary skill in the art.  Uniroyal, Inc. v. Rudkin-                
          Wiley Corp., 837 F.2d 1044, 1051, 5 USPQ2d 1434, 1438 (Fed.                 
          Cir. 1988), cert. denied, 488 U.S. 825 (1988); Ashland Oil,                 
          Inc. v. Delta Resins & Refractories, Inc.,                                  


          776 F.2d 281, 293, 227 USPQ 657, 664 (Fed. Cir. 1985), cert.                
          denied, 475 U.S. 1017 (1986); ACS Hosp. Sys., Inc. v.                       
          Montefiore Hosp., 732 F.2d 1572, 1577, 221 USPQ 929, 933 (Fed.              
          Cir. 1984).  These showings by the examiner are an essential                
          part of complying with the burden of presenting a prima facie               
          case of obviousness.  Note In re Oetiker, 977 F.2d 1443, 1445,              
          24 USPQ2d 1443, 1444 (Fed. Cir. 1992).  If that burden is met,              
          the burden then shifts to the applicant to overcome the prima               
          facie case with argument and/or evidence.  Obviousness is then              
          determined on the basis of the evidence as a whole.  See id.;               
          In re Hedges, 783 F.2d 1038, 1039, 228 USPQ 685, 686 (Fed.                  
          Cir. 1986); In re Piasecki, 745 F.2d 1468, 1472, 223 USPQ 785,              








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